14th March, 2018
Is a man's grey matter the same as a woman's? The documentary features Professor Allan Herbison and Dr Jenny Clarkson and was made with the support of NZ on Air.
9th February, 2018
Dahlia based diabetes drug developed by Physiology researcher ready for human trials
In partnership with Plant and Food Research, researchers will soon begin human trials of a drug made from dahlias.
9th January, 2018
Otago breakthrough in diabetic heart disease
The molecule responsible for heart disease in diabetics has been identified by University of Otago researchers, greatly improving chances of survival.
13th November, 2017
Otago study could mean hope for infertile couples
Crucial new information about how the brain controls fertility has been unlocked by University of Otago researchers, with their findings just published in prestigious journal Proceedings of the National Academy of Sciences of the United States of America.
13th November, 2017
Phenomenal success for Physiology researchers in latest Marsden funding round
Four 3-year project grants were awarded to Department of Physiology researchers in this year’s Marsden Fund - totalling over $3.8M.
19th March, 2018
Matt Hall, 1-yr PhD Presentation, Department of Physiology
Unless stated otherwise, Departmental Seminars are held in the Hercus D'Ath Lecture Theatre at 13:00 on the day specified.
Subscribe to our RSS feed and receive new seminar information directly.
Monday, 19th March 2018 - Hercus d'Ath Lecture Theatre at 13:00.
Swings and Roundabouts: An electrophysiological approach to lithium therapy in bipolar disorder
Oscillatory phenomena characterise human brain function at all levels, from the molecular and cellular, to neuronal networks and beyond. Bipolar disorder affects more than 50,000,000 individuals worldwide and is characterised by extreme mood oscillation (between manic and depressive states). Lithium is the first line treatment for bipolar disorder, yet remains poorly understood after >50 years as a pharmaceutical treatment. Combining electrophysiological techniques in rodent brain slices with EEG analyses in healthy human volunteers, we aim to present a model of lithium therapy in which modulation of the fundamental determinants of neuronal activity - membrane ion currents – impacts oscillation through all levels of brain function, culminating in the stabilisation of mood in bipolar patients.
Monday, 26th March 2018 - Hercus d'Ath Lecture Theatre at 13:00.
Adrenergic signalling in diabetic cardiac dysfunction
Cardiac complications are the leading cause of morbidity and mortality in the large population of type 2 diabetic patients. Adrenergic signalling is key for regulating cardiac function, and is known to be disrupted in diabetes. I will discuss alterations in adrenergic receptor sensitivity, increases in sympathetic and parasympathetic nerve activity and explore the mechanisms through which chronic beta-blockade can repair cardiac function in the type 2 Zucker Diabetic Fatty rat.
Monday, 9th April 2018 - Hercus d'Ath Lecture Theatre at 13:00.
Therapeutic modulation of microRNAs (miRs) to prevent/treat diabetic cardiomyopathy
The impact of diabetes on the development of vascular disease have been established earlier but non-ischemic cardiac complications associated with diabetes such as diabetic cardiomyopathy has received fewer attention. MicroRNAs (miRs) have recently been evolved as a key role player in diabetic heart disease. Abnormal regulation of cardiac-specific miRs lays foundation to the development of structural and functional deterioration in the later stages of the disease. Based on this evidence my project aims to therapeutically modulate miRs with the aim to prevent/treat diabetic cardiomyopathy. In particular my project will be targeting on two such miRs (miR-320 and -29a) that are abundantly expressed in cardiomyocytes. In my PhD I will aim to modulate the expression level of both these miRs using established "Locked Nucleic Acid (LNA)" system or the newly emerging CRISPR/C2c2 system. The results will lay foundation for the development of new strategies in the treatment of diabetic cardiomyopathy.
Monday, 30th April 2018 - Hercus d'Ath Lecture Theatre at 13:00.
Monday, 28th May 2018 - Hercus d'Ath Lecture Theatre at 13:00.
Monday, 11th June 2018 - Hercus d'Ath Lecture Theatre at 13:00.
My Summer Research Scholarship in the Department of Physiology was the highlight of my time at the University of Otago as I learnt many new skills, including how to carry out scientific research in a controlled manner, collecting and analyzing scientific data in an orderly fashion, and most importantly, learning to read and think critically.