University of Otago.Department of Physiology.Department of Physiology.

Jones Lab

Dr Peter Jones

Peter Jones

Senior Lecturer

Department of Physiology
Otago School of Medical Sciences
University of Otago
PO Box 913
Dunedin
New Zealand

Phone: 4703548
Fax: +64 3 479 7323

Email: pete.jones@otago.ac.nz

Member of Cardiovascular & Respiratory Physiology and Membrane & Ion Transport.

Research interests

My principal research interest is in how calcium cycling is controlled in cardiac myocytes. In particular my focus is on the mechanisms by which calcium release from intra-cellular stores (sarcoplasmic reticulum, SR) is controlled by the cardiac ryanodine receptor (RyR2). The aim of my research is to characterize how the activity of RyR2 is altered both physiologically and in disease. This is achieved using a broad spectrum of assays from molecular biology and single channel recordings, through to isolated cardiac myocytes and ultimately whole animal models.

Keywords

Arrhythmia, RyR2, calcium, sarcoplasmic reticulum, RyR1, malignant hyperthermia

Current funding

Previous funding

Collaborators

Badrilla Ltd, www.badrilla.com (characterisation of phosphor-specific cardiac antibodies)

Lab personnel

Gillian Hughes

Gillian Hughes

Janet McLay

Janet McLay

Helen Waddell

Helen Waddell

Joe Zhang

Joe Zhang


Selected publications

Commentaries & editorials

Gillian Hughes

Gillian Hughes

Assistant Research Fellow

Department of Physiology
Otago School of Medical Sciences
University of Otago
PO Box 913
Dunedin
New Zealand

Phone: 4703417
Fax: +64 3 479 7323

Email: gill.hughes@otago.ac.nz

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Janet McLay

Janet McLay

Research Technician

Department of Physiology
Otago School of Medical Sciences
University of Otago
PO Box 913
Dunedin
New Zealand

Phone: 4794211
Fax: +64 3 479 7323

Email: janet.mclay@otago.ac.nz

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Helen Waddell

Helen Waddell

Research Assistant

Department of Physiology
Otago School of Medical Sciences
University of Otago
PO Box 913
Dunedin
New Zealand

Phone: 4794211
Fax: +64 3 479 7323

Email: helen.waddell@otago.ac.nz

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Joe Zhang

Joe Zhang

PhD Student

Department of Physiology
Otago School of Medical Sciences
University of Otago
PO Box 913
Dunedin
New Zealand

Phone: 4794211
Fax: +64 3 479 7323

Email: zhazh623@student.otago.ac.nz

Thesis topic: Regulation of the cardiac ryanodine receptor.

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I am passionately devoted to the study of life, and particularly to the higher forms of life. For me the one great question that has dominated my life is: "What am I?" What is the meaning of this marvelous gift of life? The more we know, the more the mystery grows.

Sir John Eccles - The Nobel Prize in Physiology or Medicine 1963