University of Otago.Department of Physiology.Department of Physiology.

Physiology TV

An overview of Physiology at the University of Otago.

News

17th May, 2018

BMS Postgraduate Colloquium

Congratulations to all the students who presented at the BMS Postgraduate Colloquium this week.

11th April, 2018

PCOS research featured in the news

The latest exciting findings from Assoc Prof Rebecca Campbell's lab into the role of brain signalling in polycystic ovary syndrome was featured on RadioNZ on 10th April.

14th March, 2018

Is a man's grey matter the same as a woman's? The documentary features Professor Allan Herbison and Dr Jenny Clarkson and was made with the support of NZ on Air.

9th February, 2018

Dahlia based diabetes drug developed by Physiology researcher ready for human trials

In partnership with Plant and Food Research, researchers will soon begin human trials of a drug made from dahlias.

9th January, 2018

Otago breakthrough in diabetic heart disease

The molecule responsible for heart disease in diabetics has been identified by University of Otago researchers, greatly improving chances of survival.

Next Event

2nd July, 2018

Dr Justin Deniset (University of Calgary)

 
PhD Programme.

News

28th August, 2017

Dr Andrew Bahn awarded Arthritis NZ Project Grant

Dr Andrew Bahn awarded Arthritis NZ Project Grant

Congratulations to Dr Bahn who has been awarded a $60K grant for his project “Identification of oxypurinol transporters to decipher drug-drug interactions in gout treatment”.

Gout is a painful inflammation of the joins due to high serum uric acid (SUA) based mostly on an unhealthy Western diet. The gold standard for gout treatment is allopurinol. Once converted into oxypurinol, it inhibits production of uric acid in the liver and lowers SUA. Gout has been associated with many comorbidities including hypertension, which requires adjustment of allopurinol dosage. These drug-drug interactions render gout treatment with allopurinol ineffective exposing the patient to further gout attacks and the risk of life threatening side effects. As drug-drug interactions are based on competition of drugs at transport proteins we hypothesise transporters of the organic anion transporter family (OATs), which are expressed in liver and kidney, are responsible for the observed drug-drug interaction. By investigating these drug-drug interactions in primary human kidney and liver cells, Dr Bahn aims to identify allopurinol/oxypurinol transporters to resolve these drug-drug interactions and improve management of gout treatment.

Having a Summer Research Scholarship opened up a lot more opportunities for me to explore my career potentials. I strongly recommend taking up this opportunity because it definitely gave me the confidence and skills essential for my future endeavors.

Aye Thaung - Summer Research Student 2010/2011