|
|
Membrane & Ion Transport
Immunofluorescence image
of hIK1 channel (green)
(K. Hamilton)
|
Within the focus six groups are involved in investigations of the mechanisms and regulation of solute and water movement across cell membranes
and resultant pathologies. Current areas of interest include the regulation
of epithelial ion channels by binding proteins and pharmacological agents,
epithelial fluid and electrolyte transport in the
intestine, cardiac function and the control of sodium and water
handling in obesity.
Techniques:
- Fluorescent measurement of [Ca]i and pHi
- Ussing Chamber - Short Circuit Current
- Patch-Clamp
- Two-Electrode Voltage-Clamp
- MALDI (Matrix-assisted laser desorption/ionization mass spectroscopy)
- X-ray Microanalysis
- Confocal Microscopy
- Molecular Biology
- Immunohistochemistry
Personnel:
|
